ALDH1L1
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Loading...- Rabbit Anti-ALDH1L1 Recombinant Antibody (clone JU53-54) (MRO-0051-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC
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- Species Reactivity: Human
- Type: Mouse IgG3
- Application: FC, IF, IHC-P, WB
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: IHC-P, WB, IP
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- Derivation: Mouse
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1
- Application: WB, IHC, FCM
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- Derivation: Mouse
- Species Reactivity: Human, Rat
- Type: Mouse IgG1
- Application: WB, IHC, FCM
- Anti-ALDH1L1 Immunohistochemistry Kit (VS-0525-XY298)
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- Species Reactivity: Human
- Target: ALDH1L1
- Application: IHC
- Anti-Mouse ALDH1L1 Immunohistochemistry Kit (VS-0525-XY299)
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- Species Reactivity: Human, Mouse
- Target: ALDH1L1
- Application: IHC
- Anti-Rat ALDH1L1 Immunohistochemistry Kit (VS-0525-XY300)
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- Species Reactivity: Human, Mouse, Rat
- Target: ALDH1L1
- Application: IHC
- Anti-Canine ALDH1L1 Immunohistochemistry Kit (VS-0525-XY301)
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- Species Reactivity: Human, Mouse, Rat, Canine
- Target: ALDH1L1
- Application: IHC
- Mouse Anti-ALDH1L1 Recombinant Antibody (AL131) (VS-0326-YC131)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1
- Application: ELISA, IHC, FC, WB
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP⁺), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Protein class
Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Group enriched (Hepatocytes, Proximal tubular cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (ASC diff, Hep G2, Karpas-707, RPMI-8226, RT4, U-266/70)
Interaction
Homotetramer.
Molecular function
Oxidoreductase
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