


APOL1

Anti-APOL1 Products
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB
- Mouse Anti-APOL1 Recombinant Antibody (clone 2E5) (MOB-0687MZ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: FC, ICC, IP, WB
- Mouse Anti-APOL1 Recombinant Antibody (clone 6D12) (VS-0724-FY16)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IF, IP
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
- Anti-APOL1 Immunohistochemistry Kit (VS-0325-XY135)
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- Species Reactivity: Human
- Target: APOL1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Creative Biolabs uses advanced platforms to offer a diverse range of APOL1-targeted recombinant antibodies to customers worldwide. We are committed to providing exceptional, top-tier solutions that are tailored to our customers' specific needs. By constantly pushing the boundaries of research and innovation, we provide unrivaled technical support and service excellence, allowing our customers to achieve their scientific objectives efficiently and effectively.
APOL1: An Effective Target in Kidney Diseases
Apolipoprotein L1 (apoL1) is a minor component of HDL cholesterol, produced in the liver and various other tissues such as the pancreas, kidney, and brain. Each person carries two copies of the APOL1 gene, which are associated with an elevated risk of nondiabetic kidney disease and idiopathic focal segmental glomerulosclerosis (FSGS). Thus, APOL1 is recognized as a "kidney-risk" gene in specific populations, at the same time targeting APOL1 through precise therapeutics is crucial for the effective treatment of related kidney diseases.
Alternative Names
APOL1; APOL; APO-L; APOL; APOL-I; Apolipoprotein L; apolipoprotein L, 1; apolipoprotein L1; Apolipoprotein L-I; FSGS4; apolipoprotein L1-B3.
Background
Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Transporters
Membrane, Secreted (different isoforms)
Cell type enhanced (Glandular and luminal cells, Hepatocytes, Endometrial ciliated cells, Pancreatic endocrine cells)
Low immune cell specificity
Cell line enhanced (EFO-21, HDLM-2, HHSteC, RPTEC TERT1, RT4)
In plasma, interacts with APOA1 and mainly associated with large high density lipoprotein particles.
Anti-APOL1 Recombinant Antibody Products
Here is a selection of top-notch recombinant antibody products offered by Creative Biolabs. Our antibodies are renowned for their outstanding sensitivity, specificity, and purity, guaranteeing the highest quality in product delivery. We provide these products on a global scale to support research and innovation, while also offering excellent technical assistance to our customers.
Cat. No. | Product Name | Target Species | Host Species | Applications |
MOR-0218 | Hi-Affi™ Rabbit Anti-APOL1 Recombinant Antibody (clone DS218AB) | Human | Rabbit IgG | FC, ICC, IP, WB |
MOB-0687MZ | Mouse Anti-APOL1 Recombinant Antibody (clone 2E5) | Human | Mouse IgG1 | ELISA, WB |
VS3-XY86 | Mouse Anti-APOL1 Recombinant Antibody (clone 1D4) | Human | Mouse IgG1 | ELISA, WB |
ZG-0302F | Mouse Anti-ApoL1 Recombinant Antibody (ZG-0302F) | Human | Mouse IgG | ELISA, WB |
Creative Quality Control
Our dedication is to advance research and development by providing unparalleled product quality and exceptional support, empowering the biopharmaceutical community. We ensure that customer satisfaction is our top priority by vigilantly upholding a comprehensive quality management system. This guarantees that our products not only satisfy but exceed industry standards, thereby simplifying the drug development process and providing our customers with superior value.
Fig.1 Anti-APOL1 Recombinant Antibody in WB.
(Cat# ZG-0302F, Creative Biolabs).
Customer Reviews

Mouse Anti-APOL1 Recombinant Antibody (clone 2E5) (CAT#: MOB-0687MZ)
Sample: RCC-7860 whole cell lysate.
By following the recommended dilution and sample loading volume in the instructions, I achieved development results that displayed clear and specific bands, with no interference from the background. And, the batches can maintain a high level of consistency. This antibody from Creative Biolabs performs excellence in my opinion.

Mouse Anti-APOL1 Recombinant Antibody (clone 1D4) (CAT#: VS3-XY86)

Hi-Affi™ Rabbit Anti-APOL1 Recombinant Antibody (clone DS218AB) (CAT#: MOR-0218)
In addition, the provided protocol was straightforward to follow, and the antibody performed excellently under standard IF conditions without the need for any adjustments.
Anti-APOL1 Recombinant Antibody Production
Our cutting-edge bioproduction facilities (serum-free mammalian cell expression platform) support comprehensive solutions, from gene synthesis to high-yield bulk production of anti-APOL1 recombinant antibodies. Leveraging our deep expertise and proven methodologies, we deliver cost-effective and rapid turnaround services, tailored to meet the diverse needs of our customers without compromising on quality.
Featured Anti-APOL1 Recombinant Antibody Production Platforms
Fig.2 Milligram-scale anti-APOL1 recombinant antibody production.
Fig.3 Gram-scale anti-APOL1 recombinant antibody production.
Anti-APOL1 Recombinant Antibody Modalities
Creative Biolabs is dedicated to supporting the research community with an extensive array of cutting-edge recombinant antibodies. We specialize in developing anti-APOL1 antibodies in diverse formats such as full-length, Fab, and scFv. Leveraging our expertise in antibody engineering, we are well-prepared to provide customized solutions that meet the specific needs of your research projects.
Fig.4 Full-Length Anti-APOL1Recombinant Antibody Production and Modalities.
APOL1-Targeted Drug Information
Table 1. APOL1-targeted drug information.
Company | Highest Phase | Classification | Condition |
Immatics (Originator) | Phase III |
Cancer Immunotherapy Cancer Vaccines Peptides Peptide Vaccines |
Cancer, kidney (renal cell carcinoma) Cancer, kidney (renal cell carcinoma, clear cell) |
Maze Therapeutics (Originator) | Phase I | Renal Disorders | |
AstraZeneca Ionis Pharmaceuticals (Originator) |
Phase I |
Antisense Therapy Single-stranded oligodeoxyribonucleotide (DNA) |
Chronic kidney disease Nephropathy Renal and urinary system genetic disorders |
OmniAb (Originator) | Preclinical | Proteinuria | |
Maze Therapeutics (Originator) | Preclinical | Renal Disorders | |
Maze Therapeutics (Originator) | Preclinical | Renal Disorders | |
Ionis Pharmaceuticals (Originator) University of Pennsylvania (Originator) |
Preclinical |
Antisense Therapy Oligonucleotides |
Renal Disorders |
University of Georgia (UGA) (Originator) | Biological Testing |
Bispecific Antibody Fusions Cancer Immunotherapy Fusion Proteins Human Monoclonal Antibodies Polypeptides, from 41 AA Single-Chain V-Domain Antibody Fragment (scFv) |
Cancer |
Ionis Pharmaceuticals (Originator) | Biological Testing |
Antisense Therapy Single-stranded oligodeoxyribonucleotide (DNA) |
Renal Disorders |
(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)
If you would like to gain deeper insights into our anti-APOL1 recombinant antibody offerings, please don't hesitate to reach out to us. We are eager to discuss potential partnerships and provide robust support for your research projects.