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AQP5
Anti-AQP5 Recombinant Antibody Products
- Anti-AQP5 Immunohistochemistry Kit (VS-0325-XY142)
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- Species Reactivity: Human, Mouse, Rat
- Target: AQP5
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Predicted to enable identical protein binding activity and water channel activity. Acts upstream of or within camera-type eye morphogenesis; saliva secretion; and water transport. Located in several cellular components, including apical plasma membrane; basal plasma membrane; and microvillus. Is expressed in several structures, including exocrine system; lung; nucleus pulposus; oocyte; and sensory organ. Used to study dry eye syndrome. Human ortholog(s) of this gene implicated in Bothnian type palmoplantar keratoderma.
Protein class
Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Transporters
Predicted location
Membrane
Single cell type specificity
Group enriched (Late spermatids, Early spermatids)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (OE19)
Interaction
Homotetramer (PubMed:18768791, PubMed:26569106). Interacts with TRPV4; the interaction is probably indirect and regulates TRPV4 activation by hypotonicity.
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