AREL1
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Loading...- Mouse Anti-AREL1 Recombinant Antibody (VS-0326-YC1169) (VS-0326-YC1169)
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- Application: IHC, IP, WB
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For Research Use Only. Not For Clinical Use.
Background
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits apoptosis by ubiquitinating and targeting for degradation a number of proapoptotic proteins including DIABLO/SMAC, HTRA2 and SEPT4/ARTS which are released from the mitochondrion into the cytosol following apoptotic stimulation.