Mouse Anti-AREL1 Recombinant Antibody (VS-0326-YC1169)
CAT#: VS-0326-YC1169
This product is an anti-AREL1 antibody panel that contains two antibodies targeting AREL1. AREL1 is an E3 ligase that inhibits apoptosis by ubiquitinating pro-apoptotic proteins like Bak and Bax. By promoting their degradation, it raises the threshold for cell death, contributing to chemoresistance and tumor cell survival under stress. Two monoclonal antibodies, VS-0326-YC65 and VS-0326-YC66, directed against AREL1 were used for in vitro assays including Immunohistochemistry (IHC), Immunoprecipitation (IP) and Western Blot (WB).
| Sub Cat | Type | Clone | Species Reactivity | Applications | Application Notes | Size | Conjugation | Endotoxin | Purity | Fc Engineering | |
| VS-0326-YC65 | Mouse IgG2b | AR65 | Human | IHC | IHC (1/25-1/200) | ||||||
| VS-0326-YC66 | Mouse IgG2a | AR66 | Human, Rat | IP, WB | WB (1/500-1/1000), IP (1/100-1/200) |
Specifications
- Host Species
- Mouse
- Specificity
- AREL1
- Conjugate
- The unconjugated, Biotin and FITC formats are available.
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Target
- Alternative Names
- Apoptosis Resistant E3 Ubiquitin Protein Ligase 1; KIAA0317; Apoptosis-Resistant HECT-Type E3 Ubiquitin Transferase 1; Fibrosis-Inducing E3 Ligase 1; Apoptosis-Resistant E3 Ubiquitin Protein Ligase 1; EC 2.3.2.26; FIEL1;
- Gene ID
- 9870
- UniProt ID
- O15033
- Long Name
- Apoptosis Resistant E3 Ubiquitin Protein Ligase 1
- Post Translation Modifications
- Unmodified
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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