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ATP1B4
Loading...Anti-ATP1B4 Products
- AbPlus™ Anti-ATP1B4 Magnetic Beads (VS-0724-YC164) (VS-0724-YC164)
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- Target: ATP1B4
- Target Species: Human
- Application: IP, Protein Purification
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
This gene has been found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na,K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Protein class
Metabolic proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Group enriched (Skeletal myocytes, Cardiomyocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Not detected
Interaction
Associates with a SMAD7-transcriptional complex. Interacts with SNW1 and TOR1AIP1 (By similarity). According to PubMed:17592128, does not associate with known Na,K-ATPase alpha-subunits.
More Types Infomation
Related Signaling Pathways
cAMP Signaling Pathway
Related Diseases
Morphine Addiction