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BCMA

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
  • BAFF-DT immunotoxin (AGTO-L075D)
    • Species Reactivity: Human
    • Application: Cytotoxicity assay, Functional assay
  • BAFF-PE immunotoxin (AGTO-L075E)
    • Species Reactivity: Human
    • Application: Cytotoxicity assay, Functional assay

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