BRIP1

Recombinant Antibody Products Formats

Anti-BRIP1 Recombinant Antibody Products

Mouse Anti-BRIP1 Recombinant Antibody (clone 4H22) (MOB-0884MZ)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB
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Mouse Anti-BRIP1 Recombinant Antibody (VS3-FY2637) (VS3-FY2637)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: IHC, FC, ELISA
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Mouse Anti-BRIP1 Recombinant Antibody (clone 1B8F9) (VS7-HM258)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC, FCM
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Mouse Anti-BRIP1 Recombinant Antibody (clone 4C6C8) (VS7-HM259)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC, FCM
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Hi-Affi™ Rabbit Anti-BRIP1 Recombinant Antibody (clone DS386AB) (MOR-0386)
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.

The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations.

Protein class

Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Group enriched (Late spermatids, Early spermatids)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (MCF7)

Interaction

Binds directly to the BRCT domains of BRCA1 (PubMed:15125843). Interacts with the CIA complex components CIAO1, CIAO2B and MMS19 (PubMed:23585563).