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CεmX
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- Recombinant Human Anti-IgE Antibody (47H4) (PABX-114)
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: Neut, FuncS
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- Recombinant Human Anti-IgE Antibody scFv Fragment (47H4) (PABX-114-S (P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: Neut, FuncS
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- Recombinant Human Anti-IgE Antibody Fab Fragment (47H4) (PABX-114-F (E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: Neut, FuncS
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- Human Anti-CεmX Recombinant Antibody (FAMAB-0208-CN) (FAMAB-0208-CN)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1, κ
- Application: ELISA, WB, FC, Apop, Cyt
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- Human Anti-CεmX Recombinant Antibody (FAMAB-0209-CN)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1, κ
- Application: ELISA, WB, FC, Apop, Cyt
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- Human Anti-CεmX Recombinant Antibody (clone 1A8) (FAMAB-0210-CN)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1, κ
- Application: ELISA, WB, FC, Apop, Cyt
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- Human Anti-CεmX Recombinant Antibody (clone 3A6) (FAMAB-0211-CN)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1, κ
- Application: ELISA, WB, FC, Apop, Cyt
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- Mouse Anti-CεmX Recombinant Antibody scFv Fragment (FAMAB-0208-CN-S(P)) (FAMAB-0208-CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB, FC, Apop, Cyt
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- Mouse Anti-CεmX Recombinant Antibody scFv Fragment (FAMAB-0209-CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB, FC, Apop, Cyt
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- Mouse Anti-CεmX Recombinant Antibody (clone 1A8); scFv Fragment (FAMAB-0210-CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB, FC, Apop, Cyt
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- Mouse Anti-CεmX Recombinant Antibody (clone 3A6); scFv Fragment (FAMAB-0211-CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB, FC, Apop, Cyt
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- Human Anti-CεmX Recombinant Antibody Fab Fragment (FAMAB-0208-CN-F(E)) (FAMAB-0208-CN-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, WB, FC, Apop, Cyt
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- Human Anti-CεmX Recombinant Antibody Fab Fragment (FAMAB-0209-CN-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, WB, FC, Apop, Cyt
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- Human Anti-CεmX Recombinant Antibody (clone 1A8); Fab Fragment (FAMAB-0210-CN-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, WB, FC, Apop, Cyt
Compare
- Human Anti-CεmX Recombinant Antibody (clone 3A6); Fab Fragment (FAMAB-0211-CN-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, WB, FC, Apop, Cyt
Compare
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For Research Use Only. Not For Clinical Use.
Background
Membrane-bound IgE (mIgE) is part of the IgE-BCR and is essential for generating isotype-specific IgE responses. On mIgE+ B cells, the membrane-bound ε-chain (mε) exists predominantly in the long isoform, mεL, containing an extra 52 aa CεmX domain between CH4 and the C-terminal membrane-anchoring segment; the short isoform of mε, mεS, exists in minor proportions. CεmX thus provides an attractive site for immunologic targeting of mIgE+ B cells.