CACNG1

Formats

Anti-CACNG1 Recombinant Antibody Products

Rabbit Anti-CACNG1 Polyclonal Antibody (MRO-1706-CN) (MRO-1706-CN)
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC, IF, FC
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For Research Use Only. Not For Clinical Use.

CACNG1 (Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 1) is a Protein Coding gene. Diseases associated with CACNG1 include Malignant Hyperthermia and Malignant Hyperthermia Susceptibility. Among its related pathways are Cardiac conduction and NFAT and Cardiac Hypertrophy. Gene Ontology (GO) annotations related to this gene include voltage-gated calcium channel activity. An important paralog of this gene is CACNG6.

Protein class

FDA approved drug targets, Transporters

Predicted location

Membrane

Single cell type specificity

Cell type enriched (Skeletal myocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (HSkMC)

Interaction

Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.

Molecular function

Calcium channel, Ion channel, Voltage-gated channel

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