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CD133

Anti-CD133 Products
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
- Human Anti-CD133 Recombinant Antibody (clone CD133-scFv-1) (FAMAB-1639CQ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: WB, ELISA, FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC, FCM
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.