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CD300LF

This gene encodes a member of the CD300 protein family. Members of this family are cell surface glycoproteins with a single IgV-like extracellular domain, and are involved in the regulation of immune response. The encoded protein is an inhibitory receptor.
Protein class

CD markers

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Group enriched (Macrophages, monocytes, Kupffer cells, granulocytes, Hofbauer cells)

Immune cell specificity

Immune cell enhanced (eosinophil)

Cell line specificity

Group enriched (THP-1, U-937)

Interaction

Interacts with PTPN6/SHP-1 in a tyrosine phosphorylation dependent manner (PubMed:15184070, PubMed:15549731). Interacts with IL4R (By similarity).

Molecular function

Receptor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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