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CKM

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Anti-CKM Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.
Protein class

Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enriched (Cardiomyocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (SCLC-21H)

Interaction

Dimer of identical or non-identical chains, which can be either B (brain type) or M (muscle type). With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain.

Molecular function

Kinase, Transferase

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