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DEFA1

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For Research Use Only. Not For Clinical Use.


Background

Defensin, alpha 1 also known as human alpha defensin 1, human neutrophil peptide 1 (HNP-1) or neutrophil defensin 1 is a human protein that is encoded by the DEFA1 gene. Human alpha defensin 1 belongs to the alpha defensin family of antimicrobial peptides.
Protein class

Cancer-related genes, Plasma proteins, Transporters

Predicted location

Secreted

Single cell type specificity

Not detected

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (NB-4)

Interaction

Dimer (PubMed:17452329). Interacts with RETN (PubMed:15064728).

Molecular function

Antibiotic, Antimicrobial, Defensin, Fungicide

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