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EPS15
Anti-EPS15 Recombinant Antibody Products
- AbPlus™ Anti-EPS15 Magnetic Beads (VS-0724-YC565) (VS-0724-YC565)
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- Target: EPS15
- Target Species: Human
- Application: IP, Protein Purification
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- Anti-EPS15 Immunohistochemistry Kit (VS-0325-XY777)
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- Species Reactivity: Human, Rat
- Target: EPS15
- Application: IHC
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- Derivation: Phage display library
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: IHC-P, WB, ICC, IF
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- Anti-EPS15 Recombinant Soluble TCR (P14) (scTCR-133ZP-S(P))
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- Species Reactivity: Mouse
- Epitope: KAKYDAIFD
- MHC: HLA A*02
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- Recombinant Anti-EPS15 Soluble TCR (P14) (ZIP-Fos/ZIP-Jun) (VS-0622-YF902)
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- Species Reactivity: Mouse
- Epitope: KAKYDAIFD
- MHC: HLA A*02
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- Recombinant Anti-EPS15 Soluble TCR (P14) (C-Cys) (VS-0622-YF3610)
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- Species Reactivity: Mouse
- Epitope: KAKYDAIFD
- MHC: HLA A*02
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- Recombinant Anti-EPS15 Soluble TCR (P14) (KIH) (VS-0622-YF6318)
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- Species Reactivity: Mouse
- Epitope: KAKYDAIFD
- MHC: HLA A*02
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For Research Use Only. Not For Clinical Use.
This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2009]
Protein class
Cancer-related genes, Disease related genes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Oligodendrocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with SGIP1 (PubMed:26822536). Interacts with HGS; the interaction bridges the interaction of STAM or STAM2 with EPS15. Isoform 2 interacts with HGS and AP2A2. Part of a complex at least composed of EPS15, HGS, and either STAM or STAM2. Binds AP2A2. Interacts with AP2B1; clathrin competes with EPS15. Binds STON2. Interacts (via its SH3-binding sites) with CRK. Interacts with SH3BP4/TTP. Interacts with ERBB2. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2. Interacts (via UIM repeats) with CORO7 (when ubiquitinated at 'Lys-472'). Interacts (via UIM domains) with UBQLN1 (via ubiquitin-like domain) and can interact with both the ubiquitinated and the non-ubiquitinated forms of UBQLN1. Interacts with UBQLN2 (By similarity) (PubMed:10757979, PubMed:11062555, PubMed:12551915, PubMed:16159959, PubMed:16314522, PubMed:16325581, PubMed:16903783, PubMed:18199683, PubMed:18200045, PubMed:18362181, PubMed:20448150, PubMed:21762413, PubMed:22484487, PubMed:22648170, PubMed:24768539, PubMed:8662907, PubMed:9721102, PubMed:9723620). Interacts with REPS2; the interaction is direct (PubMed:10393179). Interacts with EPN1; the interaction is direct (PubMed:9723620, PubMed:10393179). (Microbial infection) Interacts with vaccinia virus protein A36.
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