+ Filter
Loading...
ERBIN
Loading...Anti-ERBIN Products
- Mouse Anti-ERBIN Recombinant Antibody (VS3-WK1110) (VS3-WK1110)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
Compare
- Mouse Anti-ERBIN Recombinant Antibody (VS3-FY2932) (VS3-FY2932)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: WB
Compare
- PDZ domain scaffold protein anti-Human ERBIN (SPD-L161)
-
- Scaffold Name: PDZ domain
- Target: ERBIN
- Species Reactivity: Human
- Derivation: Phage display
Compare
- Anti-ERBIN Immunohistochemistry Kit (VS-0325-XY780)
-
- Species Reactivity: Human, Mouse, Rat
- Target: ERBIN
- Application: IHC
Compare
View More Products
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
Background
This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Glandular and luminal cells, Alveolar cells type 1, Endometrial ciliated cells, dendritic cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with ERBB2, BPAG1 and ITGB4 (PubMed:10878805, PubMed:11375975, PubMed:12444095). May favor the localization of ERBB2, by restricting its presence to the basolateral membrane of epithelial cells. Also found to interact with ARVCF and delta catenin (PubMed:11821434). Interacts (via C-terminus) with DST Isoform 3 (via N-terminus) (PubMed:11375975). Interacts with NOD2 (via CARD domain) (PubMed:16203728).
More Types Infomation