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FCMR

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For Research Use Only. Not For Clinical Use.


Background

Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009 [PubMed 19858324]; Shima et al., 2010 [PubMed 20042454]).[supplied by OMIM, Jul 2010]
Predicted location

Intracellular, Membrane, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (B-cells, NK-cells, T-cells, dendritic cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Group enriched (RPMI-8226, U-266/70)

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