Mouse Anti-FCMR scFv-Fc Chimera (VS-0325-FY120)
CAT#: VS-0325-FY120
The anti-FCMR scFv-Fc antibody targets FCMR (CD32B), an Fcγ receptor involved in immune regulation and B-cell signaling. It is useful for studying the role of FCMR in immune tolerance, autoimmunity, and B-cell biology.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol & focal adhesion sites.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3910/if_selected.jpg
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Specifications
- Immunogen
- Human FcμR protein.
- Host Species
- Mouse
- Type
- Mouse IgG1, scFv-Fc
- Specificity
- Human FCMR
- Species Reactivity
- Human
- Clone
- HM7
- Applications
- Western Blot, Inhibition, Flow Cytometry
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Flow Cytometry: 10 μg/mL
Target
- Alternative Names
- Fc Fragment Of IgM Receptor; Regulator Of Fas-Induced Apoptosis Toso; Fas Apoptotic Inhibitory Molecule 3; IgM Fc Fragment Receptor; FAIM3; TOSO; Immunoglobulin Mu Fc Receptor; IgM Fc Receptor; Fc Mu Receptor
- Gene ID
- 9214
- UniProt ID
- O60667
- Long Name
- Fc Fragment Of IgM Receptor
- Cellular Localization
- Cell membrane; Early endosome membrane; Golgi apparatus, trans-Golgi network membrane; Lysosome membrane
- Post Translation Modifications
- Phosphorylated on both Tyr and Ser residues.
O-glycosylated.
Sialylated.
O-linked glycans regulate trafficking to the plasma membrane.
Modification sites at PhosphoSitePlus
Modification sites at neXtProt
Glycosylation from GlyGen 2 sites, 2 O-linked glycans (2 sites)
- Protein Refseq
- XP_047290287.1; XP_047290290.1; XP_054195589.1; XP_054195590.1; NP_001135945.1
- Function
- FCMR (Fc mu receptor) is a receptor that binds to IgM antibodies, playing a role in immune complex clearance and B cell signaling. It influences immune responses and is implicated in autoimmune diseases.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
See other products for "FCMR"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-153CQ | Anti-Human FCMR Recombinant Antibody (A38) | WB, IP | |
| TAB-154CQ | Anti-Human FCMR Recombinant Antibody (6E9) | ELISA, FC, WB | |
| TAB-153CQ-S(P) | Anti-Human FCMR Recombinant Antibody scFv Fragment (A38) | WB, IP | |
| TAB-153CQ-F(E) | Anti-Human FCMR Recombinant Antibody Fab Fragment (A38) | WB, IP | |
| TAB-154CQ-F(E) | Anti-Human FCMR Recombinant Antibody Fab Fragment (6E9) | ELISA, FC, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1241 | Hi-Affi™ Rabbit Anti-FCMR Recombinant Antibody (clone DS1241AB) | WB, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0001CQ | Human Anti-FCMR Recombinant Antibody (HPAB-0001CQ) | ELISA, FC | Human IgG1, κ |
| HPAB-0002CQ | Human Anti-FCMR Recombinant Antibody (HPAB-0002CQ) | ELISA, FC | Human IgG1 |
| FAMAB-0547WJ | Mouse Anti-FCMR Recombinant Antibody (FAMAB-0547WJ) | ELISA, WB, IF, Inhib | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0001CQ-S(P) | Human Anti-FCMR Recombinant Antibody; scFv Fragment (HPAB-0001CQ-S(P)) | ELISA, FC | Human scFv |
| HPAB-0002CQ-S(P) | Human Anti-FCMR Recombinant Antibody; scFv Fragment (HPAB-0002CQ-S(P)) | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0001CQ-F(E) | Human Anti-FCMR Recombinant Antibody; Fab Fragment (HPAB-0001CQ-F(E)) | ELISA, FC | Human Fab |
| HPAB-0002CQ-F(E) | Human Anti-FCMR Recombinant Antibody; Fab Fragment (HPAB-0002CQ-F(E)) | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY101 | AbPlus™ Anti-FCMR Magnetic Beads (A38) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC239 | Recombinant Anti-FCMR Vesicular Antibody, EV Displayed (VS-0425-YC239) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2489 | Anti-FCMR Immunohistochemistry Kit | IHC |
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