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Fc P329G LALA

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For Research Use Only. Not For Clinical Use.


A P329G mutation in the Fc together with L234A-L235A (LALA) mutations that disrupt the interaction with Fcγ-receptors (FcγRs) while maintaining the binding to neonatal Fc-receptor (nFcR) and therefore wildtype-antibody-like pharmacokinetics in patients.
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