Frizzled receptor

Frizzled receptors are a family of G protein-coupled receptors that are involved in the Wnt signaling pathway. The Wnt pathway plays a critical role in embryonic development, cell proliferation, differentiation, and tissue homeostasis. Frizzled receptors bind to Wnt ligands, triggering a cascade of intracellular signals that regulate gene expression and cell fate. Aberrant Wnt signaling has been implicated in various diseases, including cancer and developmental disorders. Understanding the functions of Frizzled receptors and the Wnt pathway is essential for developing therapeutic strategies to modulate these pathways in disease conditions.