Anti-Human Frizzled receptor Recombinant Antibody (Vantictumab) (CAT#: TAB-880)
Recombinant human monoclonal antibody expressed in CHO binding to human Frizzled receptor. Vantictumab is a monoclonal antibody designed for the treatment of cancer.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 Anti-Human Frizzled receptor Antibody (TAB-880) in SDS-PAGE
Lane 1: Non-reduced mAb
Lane 2: Reduced mAb
Figure 2 Anti-Human Frizzled receptor Antibody (TAB-880) in HPLC
SEC-HPLC analysis of TAB-880 shows that the purity is more than 95%.
Figure 3 Anti-Human Frizzled receptor Antibody (TAB-880) in ELISA
ELISA analysis of TAB-880 was performed by coating with Recombinant Human Frizzled-2/FZD2 Protein.
The secondary antibody: HRP Mouse Anti-His tag
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- IgG2 - lambda
- Species Reactivity
- Human
- Applications
- Inhib, Cyt
- CAS
- 1345009-45-1
- Generic Name
- Vantictumab
- MW
- 142.5 kDa
- Related Disease
- Solid tumors
Product Property
- Purity
- >95.0% as determined by analysis by SDS-PAGE.
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Applications
- Application Notes
- The Human Frizzled receptor antibody has been reported in applications of Inhibition, Cytotoxicity.
Inhib: 25 mg/kg.
Cyt: 25 mg/kg.
Target
- Alternative Names
- Vantictumab;1345009-45-1;OMP-18R5;FZD1;frizzled family receptor 1;frizzled (Drosophila) homolog 1 , frizzled 1, seven transmembrane spanning receptor , frizzled homolog 1 (Drosophila);frizzled-1;DKFZp564G072;frizzled;Drosophila;homolog of;1;Wnt receptor;f
- Gene ID
- 8321
- UniProt ID
- Q9UP38
Related Resources
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Vantictumab"
Afuco™ Anti-Frizzled Receptor ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-880)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant human monoclonal antibody expressed in CHO binding to human Frizzled receptor. It is a monoclonal antibody designed for the treatment of cancer.
DrugMonitor™ Anti-Vantictumab Antibody (VS-1224-YC1274)Vantictumab has been used in trials for treating solid tumors and pancreatic cancer, including stage IV pancreatic cancer. The DrugMonitor™ Anti-Vantictumab Antibody (VS-1224-YC1274) is an anti-drug antibody (ADA) against Vantictumab. This drug-based antibody is raised in mice immunized with the Vantictumab. The anti-Vantictumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Vantictumab in samples.
See other products for "Frizzled receptor"
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CAT | Product Name | Application | Type |
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NAB-1026-sdAb | Recombinant Anti-Human Frizzled receptor VHH Single Domain Antibody | IP, FC, ChiP, Neut | Llama VHH |
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Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-880, RRID: AB_3112013)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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