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GBP2
Anti-GBP2 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Glandular and luminal cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (ASC diff, EFO-21, HDLM-2, HUVEC TERT2, RT4)
Interaction
Homodimer; homodimerization occurs upon GTP-binding and is required for the association with membranous structures. Heterodimer with other family members, including GBP1, GBP3, GBP4 and GBP5.
Molecular function
Hydrolase
More Types Infomation
Related Diseases
Gastric Cancer