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GC

Anti-GC Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein class

Metabolic proteins, Plasma proteins

Predicted location

Secreted

Single cell type specificity

Group enriched (Hepatocytes, Cholangiocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (HL-60, RH-30, SiHa, U-698)

Interaction

Associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes. Interacts with LRP2; the interaction is required for renal uptake of GC in complex with 25-hydroxyvitamin D3 (By similarity).

Molecular function

Actin-binding

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