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GIPr

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For Research Use Only. Not For Clinical Use.


Background

Enables gastric inhibitory peptide receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and positive regulation of insulin secretion. Acts upstream of or within endocrine pancreas development. Is active in plasma membrane. Is expressed in cortical plate; foregut-midgut junction; neck; and thyroid gland. Human ortholog(s) of this gene implicated in cardiovascular system disease; diabetes mellitus; obesity; and type 2 diabetes mellitus. Orthologous to human GIPR (gastric inhibitory polypeptide receptor).
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