GPIIb-IIIa
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Loading...- Human Anti-GPIIb-IIIa Recombinant Antibody (HPAB-0979WJ) (HPAB-0979WJ)
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- Species Reactivity: Human
- Type: Human IgM
- Application: ELISA
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- Human Anti-GPIIb-IIIa Recombinant Antibody; scFv Fragment (HPAB-0979WJ-S(P)) (HPAB-0979WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Human Anti-GPIIb-IIIa Recombinant Antibody; Fab Fragment (HPAB-0979WJ-F(E)) (HPAB-0979WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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For Research Use Only. Not For Clinical Use.
Background
Glycoprotein IIb/IIIa (GPIIb/IIIa, also known as integrin αIIbβ3) is an integrin complex found on platelets. It is a receptor for fibrinogen and von Willebrand factor and aids platelet activation. The complex is formed via calcium-dependent association of gpIIb and gpIIIa, a required step in normal platelet aggregation and endothelial adherence.