H2BC12
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Loading...- Anti-H2BC12 Immunohistochemistry Kit (VS-0525-XY3020)
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- Species Reactivity: Human
- Target: H2BC12
- Application: IHC
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- Anti-Mouse H2BC12 Immunohistochemistry Kit (VS-0525-XY3021)
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- Species Reactivity: Human, Mouse, Rat
- Target: H2BC12
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
H2BC12: Encodes histone H2B family member. It participates in nucleosome formation and chromatin organization. The protein regulates gene expression and DNA accessibility. Dysregulation affects epigenetic control.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Syncytiotrophoblasts, Extravillous trophoblasts, Cytotrophoblasts, Hofbauer cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (K-562, SiHa, U-2 OS, U-266/84)
Interaction
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Molecular function
Antibiotic, Antimicrobial, DNA-binding
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