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HFE
Loading...Anti-HFE Products
- Mouse Anti-HFE Recombinant Antibody (clone 3F1) (VS3-XY802)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, ICC
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- Mouse Anti-HFE Recombinant Antibody (clone 23H3) (MOB-2157z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, FC, ICC, IF, IHC
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IP
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- Mouse Anti-HFE Monoclonal Antibody (VS7-0425-WR24) (VS7-0425-WR24)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IF, ICC, ELISA
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. [provided by RefSeq, May 2022]
Protein class
Disease related genes, Human disease related genes
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Kupffer cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (A549, T-47d)
Interaction
Binds TFR through the extracellular domain in a pH-dependent manner.
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