HIP1R

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For Research Use Only. Not For Clinical Use.


Background

HIP1R (Huntingtin Interacting Protein 1 Related) is a Protein Coding gene. Among its related pathways are Clathrin derived vesicle budding and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include actin binding and phosphatidylinositol binding. An important paralog of this gene is HIP1.
Protein class

Cancer-related genes

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Oligodendrocyte precursor cells, Astrocytes, Oligodendrocytes)

Immune cell specificity

Immune cell enhanced (naive B-cell, memory B-cell)

Cell line specificity

Low cell line specificity

Interaction

Homodimer (By similarity). Interacts with actin; homodimerization promotes actin binding (PubMed:16415883). Interacts with CLTB (PubMed:11889126, PubMed:15533940). Interacts with HIP1 (PubMed:11889126). Interacts (via ENTH and I/LWEQ domains) with BCL2L10 (PubMed:19255499).

Molecular function

Actin-binding

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