Enzymes, Metabolic proteins, Plasma proteins
Membrane
Cell type enhanced (Oligodendrocytes)
Immune cell enriched (basophil)
Cell line enhanced (HDLM-2)
Interacts with CREB1, SIAH1, WSB1, CBX4, TRADD, p53/TP53, TP73, TP63, CREBBP, DAXX, P53DINP1, SKI, SMAD1, SMAD2 and SMAD3, but not SMAD4. Interacts with ATF1, PML, RUNX1, EP300, NKX1-2, NKX2-5, UBE2I, HMGA1, CTBP1, AXIN1, NLK, MYB, POU4F1, POU4F2, POU4F3, UBE2I, UBL1 and ZBTB4. Probably part of a complex consisting of p53/TP53, HIPK2 and AXIN1. Interacts with SP100; positively regulates TP53-dependent transcription. Interacts with SUMO1P1/SUMO5 (PubMed:27211601). (Microbial infection) Interacts with Hantaan hantavirus nucleoprotein. (Microbial infection) Interacts with Seoul hantavirus nucleoprotein.
Kinase, Serine/threonine-protein kinase, Transferase
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For Research Use Only. Not For Clinical Use.