HistoneH3
Anti-HistoneH3 Recombinant Antibody Products
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- Species Reactivity: Human, Rat, Rabbit, Mouse
- Type: Mouse IgG2b
- Application: ELISA, WB, IHC, IP
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For Research Use Only. Not For Clinical Use.
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.