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IGHD
Anti-IGHD Recombinant Antibody Products
- Mouse Anti-IGHD Recombinant Antibody (clone IgD26) (FAMAB-1160CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FACS, WB, IHC
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- Mouse Anti-IGHD Antibody (clone IgD26), mRNA (FAMAB-1160CQ-mRNA)
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- Species Reactivity: Human
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For Research Use Only. Not For Clinical Use.
IGHD (Immunoglobulin Heavy Constant Delta) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include antigen binding.
Protein class
Immunoglobulin genes
Predicted location
Intracellular, Membrane, Secreted (different isoforms)
Single cell type specificity
Group enriched (Plasma cells, T-cells, B-cells)
Immune cell specificity
Group enriched (naive B-cell, memory B-cell)
Cell line specificity
Group enriched (Daudi, U-698)
Interaction
Immunoglobulins are composed of two identical heavy chains and two identical light chains; disulfide-linked (PubMed:20176268). An IgD molecule contains thus a delta heavy chain combined with either a kappa or a lambda light chains. Kappa light chains are found predominantly on the membrane IgD (mIgD) form and lambda on the secreted IgD (sIgD) form, this fact is poorly understood. Membrane-bound IgD molecules are non-covalently associated with a heterodimer of CD79A and CD79B (PubMed:11282392).
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