Integrin α4β7
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- Derivation: Phage display library
- Type: Human antibody
- Application: ELISA, FC
- Anti-human Integrin α4β7 scFv Fragment (J19) (TAB-718LC-S(P))
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- Derivation: Phage display library
- Type: Human antibody
- Application: ELISA, FC
- Anti-human Integrin α4β7 Fab Fragment (J19) (TAB-718LC-F(E))
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- Derivation: Phage display library
- Type: Human antibody
- Application: ELISA, FC
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- Species Reactivity: Mouse
- Type: IgG2a, κ
- Application: FC, BL, IHC-Fr
- Human Anti-Integrin α4β7 Recombinant Antibody (HPAB-0844-CN) (HPAB-0844-CN)
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- Derivation: Human
- Species Reactivity: Monkey
- Type: Human IgG, κ
- Application: FC, Neut
- Human Anti-Integrin α4β7 Recombinant Antibody (HPAB-0845-CN) (HPAB-0845-CN)
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- Derivation: Human
- Species Reactivity: Monkey
- Type: Human IgG, κ
- Application: FC, Neut
- Human Anti-Integrin α4β7 Recombinant Antibody (HPAB-0846-CN) (HPAB-0846-CN)
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- Derivation: Human
- Species Reactivity: Monkey
- Type: Human IgG, κ
- Application: FC, Neut
- Recombinant Anti-Integrin α4β7 Antibody (MOB-583)
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- Derivation: Mouse
- Type: IgG
- Application: ELISA, WB, Neut, FuncS
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- Derivation: Human
- Type: IgG
- Application: RIA, IF, FuncS
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- Species Reactivity: Mouse
- Type: Rat IgG2a, κ
- Application: FC, FuncS, Neut
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- Derivation: Human
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Recombinant Human Anti-Integrin α4β7 Antibody Fab Fragment (MHH-583-F(E))
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- Derivation: Human
- Type: Fab
- Application: ELISA, WB, FC, FuncS
- Recombinant Human Anti-Integrin α4β7 Antibody scFv Fragment (MHH-583-S(P))
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- Derivation: Human
- Type: scFv
- Application: ELISA, WB, Neut, FuncS
- Recombinant Anti-Integrin α4β7 Antibody Fab Fragment (MOB-583-F(E))
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- Derivation: Mouse
- Type: Fab
- Application: ELISA, IF, FuncS
- Recombinant Anti-Integrin α4β7 Antibody scFv Fragment (MOB-583-S(P))
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- Derivation: Mouse
- Type: scFv
- Application: WB, IP, FuncS
- Human Anti-Integrin α4β7 Recombinant Antibody; scFv Fragment (HPAB-0844-CN-S(P)) (HPAB-0844-CN-S(P))
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- Derivation: Human
- Species Reactivity: Monkey
- Type: Human scFv
- Application: FC, Neut
- Human Anti-Integrin α4β7 Recombinant Antibody; scFv Fragment (HPAB-0845-CN-S(P)) (HPAB-0845-CN-S(P))
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- Derivation: Human
- Species Reactivity: Monkey
- Type: Human scFv
- Application: FC, Neut
- Human Anti-Integrin α4β7 Recombinant Antibody; scFv Fragment (HPAB-0846-CN-S(P)) (HPAB-0846-CN-S(P))
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- Derivation: Human
- Species Reactivity: Monkey
- Type: Human scFv
- Application: FC, Neut
- Human Anti-Integrin α4β7 Recombinant Antibody; Fab Fragment (HPAB-0844-CN-F(E)) (HPAB-0844-CN-F(E))
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- Derivation: Human
- Species Reactivity: Monkey
- Type: Human Fab
- Application: FC, Neut
- Human Anti-Integrin α4β7 Recombinant Antibody; Fab Fragment (HPAB-0845-CN-F(E)) (HPAB-0845-CN-F(E))
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- Derivation: Human
- Species Reactivity: Monkey
- Type: Human Fab
- Application: FC, Neut
- Human Anti-Integrin α4β7 Recombinant Antibody; Fab Fragment (HPAB-0846-CN-F(E)) (HPAB-0846-CN-F(E))
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- Derivation: Human
- Species Reactivity: Monkey
- Type: Human Fab
- Application: FC, Neut
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- Species Reactivity: Monkey
- Type: Human IgG kappa
- Application: FC, Neut
- Human Anti-Integrin α4β7 Antibody (J19), CHO Stable Cell Pool (VS-1025-QX318)
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- Host Species: Human
- Target: Integrin α4β7
- Species Reactivity: Human
- Antibody Type: Human IgG1, λ
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For Research Use Only. Not For Clinical Use.
Background
Integrins are transmembrane receptors that are the bridges for cell-cell and cell-extracellular matrix (ECM) interactions. When triggered, integrins in turn trigger chemical pathways to the interior (signal transduction), such as the chemical composition and mechanical status of the ECM, which results in a response (activation of transcription) such as regulation of the cell cycle, cell shape, and/or motility; or new receptors being added to the cell membrane. This allows rapid and flexible responses to events at the cell surface, for example to signal platelets to initiate an interaction with coagulation factors.

