Integrin αvβ3
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Loading...- Human Anti-integrin αvβ3 Recombinant Antibody (clone Bc-12) (VS-0423-XY23)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, IF
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- Human Anti-integrin αvβ3 Recombinant Antibody (clone Bc-15) (VS-0423-XY24)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, IF
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For Research Use Only. Not For Clinical Use.
Background
αVβ3 is a type of integrin that is a receptor for vitronectin. It consists of two components, integrin alpha V and integrin beta 3 (CD61), and is expressed by platelets. Furthermore, it is a receptor for phagocytosis on macrophages or dendritic cells. Integrin αVβ3 is potential drug target because abnormal expression of v3 is linked to the development and progression of various diseases.