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KCNK4

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For Research Use Only. Not For Clinical Use.


Background

Predicted to enable identical protein binding activity and monoatomic cation channel activity. Involved in detection of mechanical stimulus involved in sensory perception of touch; sensory perception of pain; and sensory perception of temperature stimulus. Predicted to be located in node of Ranvier. Predicted to be part of potassium channel complex. Predicted to be active in plasma membrane. Is expressed in 2-cell stage embryo; blastocyst; early conceptus; secondary oocyte; and spermatid. Orthologous to human KCNK4 (potassium two pore domain channel subfamily K member 4).
KCNK4
Protein class

Disease related genes, Human disease related genes, Potential drug targets, Voltage-gated ion channels

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Endometrial stromal cells, Excitatory neurons, Muller glia cells, Extravillous trophoblasts, Horizontal cells, Astrocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

Interaction

Homodimer; disulfide-linked.

Molecular function

Ion channel, Potassium channel, Voltage-gated channel

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