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KIF4A
Loading...Anti-KIF4A Products
- Recombinant Anti-Human KIF4A Antibody scFv Fragment (MOB-3064z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, IP, FuncS
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- Recombinant Anti-Human KIF4A Antibody Fab Fragment (MOB-3064z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB, Neut, FuncS
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- Anti-Mouse KIF4A Immunohistochemistry Kit (VS-0525-XY3776)
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- Species Reactivity: Human, Mouse
- Target: KIF4A
- Application: IHC
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- Anti-KIF4A Immunohistochemistry Kit (VS-0525-XY3775)
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- Species Reactivity: Human
- Target: KIF4A
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the kinesin 4 subfamily of kinesin related proteins. The encoded protein is an ATP dependent microtubule-based motor protein that is involved in the intracellular transport of membranous organelles. This protein also associates with condensed chromosome arms and may be involved in maintaining chromosome integrity during mitosis. This protein may also be involved in the organization of the central spindle prior to cytokinesis. A pseudogene of this gene is found on chromosome X. [provided by RefSeq, Mar 2010]
Protein class
Disease related genes, Human disease related genes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Erythroid cells, Endometrial ciliated cells, Granulosa cells, Extravillous trophoblasts)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Low cell line specificity
Interaction
Interacts with the cytosolic iron-sulfur protein assembly (CIA) complex components CIAO2B and MMS19; the interactions facilitate the transfer of Fe-S clusters to KIF4A to ensure proper localization of KIF4A to mitotic machinery components (PubMed:29848660). Interacts (via C-terminus) with unphosphorylated PRC1 (via N-terminus); the interaction is required for the progression of mitosis (PubMed:15297875, PubMed:15625105, PubMed:29848660).
Molecular function
DNA-binding, Motor protein
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