KLF1
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Loading...- Mouse Anti-KLF1 Recombinant Antibody (clone 1B6A3) (VS7-0425-WR225)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC, FC
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- Anti-KLF1 Immunohistochemistry Kit (VS-0525-XY3791)
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- Species Reactivity: Human
- Target: KLF1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.