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KLK5
Loading...Anti-KLK5 Products
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: ICC, IF, FC, WB
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- Anti-Mouse KLK5 Immunohistochemistry Kit (VS-0525-XY3808)
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- Species Reactivity: Mouse
- Target: KLK5
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.
Protein class
Cancer-related genes, Enzymes
Predicted location
Secreted
Single cell type specificity
Group enriched (Late spermatids, Early spermatids)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (A-431, HaCaT)
Interaction
Interacts with SPINK9.
Molecular function
Hydrolase, Protease, Serine protease
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