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Keap1-Nrf2-ARE Pathway

Anti-Keap1-Nrf2-ARE Pathway Products

Keap1-Nrf2-ARE Pathway Antibody Panel (HMOX1, KEAP1, NFE2L2, NQO1) (VS-0725-YC36)
- Species Reactivity: Human
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For Research Use Only. Not For Clinical Use.

Background

The Keap1-Nrf2-ARE pathway is arguably the most crucial cellular defense mechanism against oxidative stress, electrophilic insults, and inflammation. It functions as a master regulator, orchestrating the inducible expression of a vast network of genes encoding antioxidant enzymes, detoxification proteins, and other cytoprotective factors. Understanding this pathway is vital for appreciating cellular resilience and for developing therapeutic strategies for a wide range of diseases.