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Laminin-332

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For Research Use Only. Not For Clinical Use.


Background

The antibodies against various domains of laminin-332 reduce the adhesion and matrix binding properties of laminin-332, inhibiting tumor growth and metastasis in vivo. LN-332 is up-regulated in various epithelial cancers, including colon, gastric, mammary duct and squamous cell carcinomas, as well as melanomas, but not in mesenchymal cancers.
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