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MLXIPL
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Anti-MLXIPL Products
- Mouse Anti-MLXIPL Recombinant Antibody (clone 7A10) (VS3-XY1077)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB
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- Mouse Anti-MLXIPL Recombinant Antibody (VS3-FY2804) (VS3-FY2804)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ICC, ELISA
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- Mouse Anti-MLXIPL Monoclonal Antibody (clone 5D12D1) (VS7-0425-WR395)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ICC
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- Anti-MLXIPL Immunohistochemistry Kit (VS-0525-XY4425)
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- Species Reactivity: Human
- Target: MLXIPL
- Application: IHC
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- Anti-Mouse MLXIPL Immunohistochemistry Kit (VS-0525-XY4426)
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- Species Reactivity: Human, Mouse, Rat, Rat
- Target: MLXIPL
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.
Protein class
Disease related genes, Human disease related genes, Plasma proteins, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Group enriched (Hepatocytes, Proximal enterocytes, Enteroendocrine cells, Cholangiocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (Hep G2, K-562, SCLC-21H, T-47d)
Interaction
Binds DNA as a heterodimer with TCFL4/MLX.
Molecular function
DNA-binding, Repressor
More Types Infomation