Mouse Anti-MLXIPL Recombinant Antibody (VS3-FY2804)

CAT#: VS3-FY2804

This anti-MLXIPL antibody is a mouse recombinant monoclonal antibody that has been meticulously designed to target the human MLXIPL protein. The calculated molecular weight of the protein is about 93.1 kDa. The optimal dilution for this antibody is Immunocytochemistry (1/50-1/200) and ELISA (1/1000-1/10000).

Gene Expression
Figure 1 IF staining of human cell line Hep G2 Figure 2 RNA cell line category: Cell line enhanced (Hep G2, K-562, SCLC-21H, T-47d)

Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Human MLXIPL
  • Species Reactivity
  • Human
  • Applications
  • Immunocytochemistry, ELISA
  • Conjugate
  • Unconjugated, FITC
  • MW
  • The molecular weight of the target protein is approximately 93.1 kDa.
  • Related Disease
  • Williams-Beuren Syndrome and Metabolic Dysfunction-Associated Steatotic Liver Disease

Product Property

  • Clonality
  • Monoclonal Antibody
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Immunocytochemistry: 1/50-1/200
    ELISA: 1/1000-1/10000

Target

  • Alternative Names
  • MLX Interacting Protein Like; Williams-Beuren Syndrome Chromosomal Region 14 Protein; WS Basic-Helix-Loop-Helix Leucine Zipper Protein; Carbohydrate Response Element Binding Protein; Williams Beuren Syndrome Chromosome Region 14; Class D Basic Helix-Loop-Helix Protein 14; WBSCR14; WS-BHLH; BHLHd14; CHREBP; MIO
  • Cellular Localization
  • Nucleus
  • Post Translation Modifications
  • Phosphorylation at Ser-556 by AMPK inactivates the DNA-binding activity. (Q9NP71-MLXPL_HUMAN)
    Modification sites at PhosphoSitePlus (Q9NP71)
    Modification sites at neXtProt (NX_Q9NP71)
    Glycosylation from GlyGen (Q9NP71) 4 sites, 1 O-linked glycan (4 sites)
  • Function
  • Binds DNA as a heterodimer with MLX/TCFL4 and activates transcription.
    Binds to the canonical E box sequence 5'-CACGTG-3'.
    Plays a role in transcriptional activation of glycolytic target genes.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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