Mouse Anti-MLXIPL Recombinant Antibody (VS3-FY2804) (CAT#: VS3-FY2804)
This anti-MLXIPL antibody is a mouse recombinant monoclonal antibody that has been meticulously designed to target the human MLXIPL protein. The calculated molecular weight of the protein is about 93.1 kDa. The optimal dilution for this antibody is Immunocytochemistry (1/50-1/200) and ELISA (1/1000-1/10000).
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/64640/1294_D5_3_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/64640/1294_D5_3_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (Hep G2, K-562, SCLC-21H, T-47d)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000009950-MLXIPL
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000009950-MLXIPL
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human MLXIPL
- Species Reactivity
- Human
- Applications
- Immunocytochemistry, ELISA
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 93.1 kDa.
- Related Disease
- Williams-Beuren Syndrome and Metabolic Dysfunction-Associated Steatotic Liver Disease
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunocytochemistry: 1/50-1/200
ELISA: 1/1000-1/10000
Target
- Alternative Names
- MLX Interacting Protein Like; Williams-Beuren Syndrome Chromosomal Region 14 Protein; WS Basic-Helix-Loop-Helix Leucine Zipper Protein; Carbohydrate Response Element Binding Protein; Williams Beuren Syndrome Chromosome Region 14; Class D Basic Helix-Loop-Helix Protein 14; WBSCR14; WS-BHLH; BHLHd14; CHREBP; MIO
- Gene ID
- 51085
- UniProt ID
- Q9NP71
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Phosphorylation at Ser-556 by AMPK inactivates the DNA-binding activity. (Q9NP71-MLXPL_HUMAN)
Modification sites at PhosphoSitePlus (Q9NP71)
Modification sites at neXtProt (NX_Q9NP71)
Glycosylation from GlyGen (Q9NP71) 4 sites, 1 O-linked glycan (4 sites)
- Protein Refseq
- XP_011514580.1; XP_011514581.1; XP_016867752.1; XP_047276388.1
- Function
- Binds DNA as a heterodimer with MLX/TCFL4 and activates transcription.
Binds to the canonical E box sequence 5'-CACGTG-3'.
Plays a role in transcriptional activation of glycolytic target genes.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "MLXIPL"
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2152z | Mouse Anti-MLXIPL Recombinant Antibody (clone 22F4) | WB, FC, ICC, IHC | Mouse IgG1 |
| VS3-XY1077 | Mouse Anti-MLXIPL Recombinant Antibody (clone 7A10) | ELISA, WB | Mouse IgG1 |
| VS7-0425-WR395 | Mouse Anti-MLXIPL Monoclonal Antibody (clone 5D12D1) | ICC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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