Mycobacterium tuberculosis MPT64

Mycobacterium tuberculosis MPT64 is identical to the above-described MPT64, a MTBC-specific secreted protein of Mycobacterium tuberculosis. It plays a role in cell wall metabolism and is highly secreted during active infection, which underpins its utility in active tuberculosis diagnostics. Rapid tests targeting MPT64 enable quick detection of MTBC infections, supporting timely treatment initiation. Its immunogenicity also makes it a potential vaccine antigen, as it can stimulate host immune responses that target actively replicating bacteria. Given its specificity to MTBC, MPT64-based tools help avoid cross-reactivity with non-tuberculous Mycobacteria, improving diagnostic accuracy and vaccine specificity.