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NDUFV2
Loading...Anti-NDUFV2 Products
- AbPlus™ Anti-NDUFV2 Magnetic Beads (VS-0724-YC308) (VS-0724-YC308)
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- Target: NDUFV2
- Target Species: Human, Cynomolgus
- Application: IP, Protein Purification
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- Anti-NDUFV2 Immunohistochemistry Kit (VS-0525-XY4758)
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- Species Reactivity: Human
- Target: NDUFV2
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19. [provided by RefSeq, Oct 2009]
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.
Molecular function
Oxidoreductase, Translocase
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