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PAIP1

Anti-PAIP1 Products

Recombinant Mouse Anti-Human PAIP1 Antibody (MOB-1876MZ)
- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, WB
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Rabbit Anti-PAIP1 Recombinant Antibody (clone R08-8C6) (VS3-FY1814)
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-Fr, IHC-P, IF, IP
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Hi-Affi™ Recombinant Rabbit Anti-PAIP1 Monoclonal Antibody (DS2581AB) (MOR-2581)
- Derivation: Phage display library screening
- Species Reactivity: Human, Does not react with Mouse
- Type: IgG
- Application: IP, WB
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More Infomation

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For Research Use Only. Not For Clinical Use.

The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Interacts with the RRM1-RRM2 and C-terminus regions of PABPC1 in a 1:1 stoichiometry. Interacts with EIF4A. (Microbial infection) Interacts (via PAIP1M) with human SARS coronaviruses SARS-COV and SARS-COV-2 NSP3 protein (via SARS-unique domain); the interaction increases binding affinity with PABPC1.

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