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PDE10A
Loading...Anti-PDE10A Products
- Rabbit Anti-PDE10A Antibody (VS-0722-YJ173) (VS1-YJ173)
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- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: WB, IP
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- Anti-Mouse PDE10A Immunohistochemistry Kit (VS-0525-XY5263)
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- Species Reactivity: Human, Mouse, Rat
- Target: PDE10A
- Application: IHC
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- Anti-PDE10A Immunohistochemistry Kit (VS-0525-XY5262)
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- Species Reactivity: Human
- Target: PDE10A
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene.
Protein class
Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Inhibitory neurons, Excitatory neurons, Microglial cells, Oligodendrocytes, Oligodendrocyte precursor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HeLa, LHCN-M2, RT4, SH-SY5Y, TIME, U-2 OS)
Interaction
Homodimer.
Molecular function
Allosteric enzyme, Hydrolase
More Types Infomation
Related Signaling Pathways
cAMP Signaling Pathway