Anti-PDK4 Recombinant Antibody Products

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Anti-PDK4 Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs is a leading provider of high-quality recombinant antibodies against PDK4, developed to facilitate cutting-edge biological research. Our extensive product line is meticulously developed to meet the highest standards of specificity and affinity, empowering global researchers to precisely detect and characterize the pyruvate dehydrogenase kinase 4 (PDK4) protein.

PDK4: A Promising Target for Metabolic Disease and Cancer Therapy

Pyruvate Dehydrogenase Kinase 4 (PDK4) is an enzyme that plays a critical role in regulating cellular metabolism by phosphorylating and inhibiting the pyruvate dehydrogenase complex (PDC). Recent research highlights its aberrant expression in various diseases, including gastric cancer (GC), where it acts as a prognostic biomarker and promotes tumor cell proliferation and invasion. Understanding the intricate functions of PDK4 is vital for developing novel therapeutic strategies aimed at altering disease-specific metabolic pathways.

Alternative Names

Pyruvate dehydrogenase lipoamide kinase isozyme 4, mitochondrial; pyruvate dehydrogenase kinase 4.

Background

This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin. [provided by RefSeq, Jul 2008]

Anti-PDK4 rAb Products

Creative Biolabs’ anti-PDK4 recombinant antibodies offer unparalleled performance and reproducibility. Unlike traditional polyclonal antibodies, our products are produced using a proprietary recombinant expression platform, ensuring exceptional lot-to-lot consistency and a defined antigen specificity. This meticulous process results in highly purified antibodies with superior sensitivity and signal-to-noise ratio, providing you with reliable and interpretable data for your most critical experiments.

Table 1. Featured anti-PDK4 recombinant antibody products at Creative Biolabs.

Creative Quality Control

At Creative Biolabs, each batch of our anti-PDK4 recombinant antibodies undergoes a rigorous multi-step quality control process. We perform comprehensive validation using multiple platforms, including ELISA and Western blotting, to confirm product specificity and functionality. This stringent quality assurance program guarantees that every antibody you receive from Creative Biolabs is a high-performing and trustworthy tool, ready for immediate use in your research.

Customer Reviews

Excellent

A**a Sh***a
Recombinant Mouse anti-Human PDK4 Monoclonal antibody (2D3CH6) (MOB-1269CT)

The anti-PDK4 antibody from Creative Biolabs has been a game-changer for our lab. The specificity in Western blots is outstanding, and we no longer have issues with non-specific bands. The signal is strong and clear, which has saved us a significant amount of time and effort in data analysis. We will definitely be purchasing from Creative Biolabs again.

15/Mar/2024

Excellent

Mi***el
Anti-PDK4 Immunohistochemistry Kit (VS-0325-XY1608)

I used the anti-PDK4 antibody for my IHC studies on gastric cancer tissue, and the results were beautiful. The staining was incredibly clean and localized exactly where we expected. The performance and reliability of this product have allowed our team to generate high-quality, publishable data much faster than with other antibodies we've tested. A truly excellent product.

21/May/2024

Excellent

Ca***r
Mouse Anti-PDK4 Recombinant Antibody (VS3-FY2832) (VS3-FY2832)

The technical support from Creative Biolabs has been as impressive as their products. We had a few questions about protocol optimization for a new application, and their team was incredibly knowledgeable and responsive. The anti-PDK4 antibody itself works flawlessly, delivering the consistent results our project demands. I highly recommend their recombinant antibodies.

11/Oct/2024

rAb Production

Our anti-PDK4 recombinant antibodies are meticulously engineered using recombinant antibody technology and a robust mammalian expression system. This sophisticated production method allows for the selection of antibodies with superior affinity and stability. We employ a strictly controlled manufacturing process to ensure consistent product purity and biological activity, giving you confidence in the quality and performance of every antibody we provide.

Featured Anti-PDK4 Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-PDK4 recombinant antibody production.

Fig.2 Gram-scale anti-PDK4 recombinant antibody production.

rAb Modalities

To support a wide range of research needs, our anti-PDK4 antibodies are available in various formats, including different host species, isotypes, and conjugation options.

Fig.3 Full-length anti-PDK4 recombinant antibody production and modalities.

Creative Biolabs is dedicated to accelerating your scientific discoveries by providing exceptional research tools. Our anti-PDK4 recombinant antibodies are part of our commitment to delivering high-quality, reliable reagents to the global scientific community. We invite you to explore our full range of products and services. For detailed product specifications or to discuss how our anti-PDK4 antibodies can support your specific research goals, please do not hesitate to contact our expert team today.

Related Signaling Pathways

PPAR Signaling Pathway