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PLCB3
This gene encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Proximal enterocytes, Undifferentiated cells, Distal enterocytes)
Immune cell specificity
Immune cell enhanced (plasmacytoid DC)
Cell line specificity
Low cell line specificity
Interaction
Interacts with SHANK2 (By similarity). Interacts with LPAR2 (PubMed:15143197).
Molecular function
Hydrolase, Transducer
More Types Infomation
Related Signaling Pathways
cAMP Signaling Pathway
Related Diseases
Morphine Addiction
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC-P, ELISA
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For Research Use Only. Not For Clinical Use.