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PLD1
This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties.
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, RAS pathway related proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Oligodendrocytes)
Immune cell specificity
Immune cell enhanced (basophil)
Cell line specificity
Cell line enhanced (HUVEC TERT2, SK-MEL-30, TIME)
Interaction
Interacts with PIP5K1B.
Molecular function
Hydrolase
More Types Infomation
Related Signaling Pathways
Ras Signaling Pathway
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, FC, IP
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- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.