+ Filter
Loading...
PSMC4
Loading...Anti-PSMC4 Products
- AbPlus™ Anti-PSMC4 Magnetic Beads (VS-0724-YC938) (VS-0724-YC938)
-
- Target: PSMC4
- Target Species: Human
- Application: IP, Protein Purification
Compare
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: WB, ELISA, IF, IHC, IP
Compare
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, ICC, IP
Compare
- Anti-PSMC4 Immunohistochemistry Kit (VS-0325-XY1796)
-
- Species Reactivity: Human, Mouse, Rat
- Target: PSMC4
- Application: IHC
Compare
- Anti-Mouse PSMC4 Immunohistochemistry Kit (VS-0525-XY5794)
-
- Species Reactivity: Human, Mouse, Rat
- Target: PSMC4
- Application: IHC
Compare
- Anti-Human PSMC4 Immunohistochemistry Kit (VS-0525-XY5793)
-
- Species Reactivity: Human
- Target: PSMC4
- Application: IHC
Compare
View More Products
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Syncytiotrophoblasts)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits, a base containing 6 ATPases including PSMC4 and few additional components (PubMed:27428775,PubMed:27342858). Interacts with NR1I3. Interacts with PAAF1 (PubMed:15831487). Interacts with TRIM5 (PubMed:22078707). Interacts with ZFAND1 (PubMed:29804830).
More Types Infomation