Rabbit Anti-PSMC4 Recombinant Antibody (clone R44-4F-2)

CAT#: VS3-XY3479

The product is a recombinant rabbit antibody that recognizes PSMC4 (Proteasome 26S subunit, ATPase 4), which plays a key role in the maintenance of protein homeostasis. It is capable of binding to human, mouse and rat PSMC4. It has been used in a variety of applications, such as Western Blot, Immunocytochemistry or Immunofluorescence. The recommended dilutions of Western Blot and Immunofluorescence is 1/500-1/1000 and 1/50-1/200, respectively.

Specifications

  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat PSMC4
  • Species Reactivity
  • Human, Mouse, Rat
  • Clone
  • R44-4F-2
  • Applications
  • WB, ICC, IF
  • Related Disease
  • Timothy Syndrome; Episodic Ataxia, Type 2

Product Property

  • Clonality
  • Monoclonal
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Buffer
  • PBS (pH 7.4), 150 mM NaCl and 50% glycerol
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • WB: 1/500-1/1000
    IF: 1/50-1/200

Target

  • Alternative Names
  • S6; RPT3; TBP7; TBP-7; MIP224
  • Long Name
  • Proteasome 26S subunit, ATPase 4
  • Cellular Localization
  • Cytoplasm, Nucleus
  • Post Translation Modifications
  • Ubiquitination at Lys70, Lys125, Lys192, Lys217, Lys238, Lys255, and Lys273 (NX_P43686 [NX_P43686-1])
    Modification sites at PhosphoSitePlus (P43686)
    Glycosylation from GlyGen (P43686) 2 sites, 1 O-linked glycan (2 sites)
  • Function
  • Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
    This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.
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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

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Protocol & Troubleshooting

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

Isotype Control

Recommended Dilution Buffer

Secondary Antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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